The gut-brain axis is thus a critical gatekeeper in regulating feeding behavior. Bile acids are among the most abundant metabolites in the gut and act as versatile signaling molecules that relay ...

Walnut consumption modifies the fecal microbiota and metabolome, improves insulin response and reduces gut permeability in ...

The researchers also measured the abundance and composition of bile acids in the liver, stool, and plasma (the main tissues of bile acid synthesis, metabolism, and signaling, respectively) in 36 ...

More information: Yuchen Liu et al, Disrupting bile acid metabolism by suppressing Fxr causes hepatocellular carcinoma induced by YAP activation, Nature Communications (2025). DOI: 10.1038/s41467 ...

One of the hallmarks of UC is a deficiency in certain bile acids, molecules that help digest fats and regulate gut health.

Under the terms of the definitive agreement, Mirum will purchase Travere’s bile acid product portfolio for $445 million, consisting of $210 million upfront and $235 million in potential sales ...

Bile reflux differs from acid reflux, which occurs when the gastric acids flow back into the esophagus. However, a person can experience both at the same time. Bile reflux can cause several ...

In a paper in Nature, researchers at the Chinese Academy of Sciences and Xiamen University report that they have identified one such caloric restriction mimetic—a bile acid called lithocholic ...

AUGUSTA, Ga. (May 30, 2023) – It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns.