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Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.

But a significant association was only seen in BRCA1 carriers: BRCA1 carriers: HR 0.44 (95% CI 0.34-0.57) BRCA2 carriers: HR 0.85 (95% CI 0.64-1.15) As for the secondary endpoints of disease-free ...

She thought nothing of the routine genetic testing ordered by her doctor until she got an email in March 2020 revealing she was BRCA2 positive. According to the National Cancer Institute ...

Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition to develop breast cancer, ovarian, prostate, pancreatic ...

We identified the breast cancer gene BRCA2, which enabled families with a history of breast cancer to be assessed for future risk, and laid the groundwork for developing novel forms of therapy for ...

Mutations in BRCA2 — a gene known to repair damaged DNA and suppress tumor formation — can predict an individual’s predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other ...