Although less common, BCR-ABL1 can also be present in other types of leukemia. These include acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML). Researchers estimate that 25% of ...

BCR-ABL forms a dimer and/or tetramer through the coiled-coil domain in the N terminus of BCR, which is thought to promote BCR-ABL activation and oncogenesis by facilitating transphosphorylation.

ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to ...

ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be ...

to develop the first automated assay for BCR-ABL. Dr. Radich runs the Molecular Oncology Lab, a certified diagnostics lab performing rapid genetic tests for CML and acute myeloid leukemia (AML) ...