BCR-ABL forms a dimer and/or tetramer through ... mutants in Ba/F3-p210 cells increases sensitivity to imatinib To test whether the deletion mutants may affect imatinib sensitivity, the Δ248 ...
Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine ...
In chronic myelogenous leukaemia (CML), a reciprocal translocation between chromosomes 9 and 22 results in a gene encoding BCR–ABL, a fused deregulated kinase that stimulates cellular ...
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