Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.

Aspirin, a widely used anti-inflammatory drug, is known for its ability to inhibit cyclooxygenase (COX) enzymes. Previous ...

Research has led to a new understanding of how aspirin stimulates the immune system to reduce the metastasis of some early ...

polymorphism of aspirin's target; the cyclooxygenase-1 (COX-1) gene; and patient nonadherence. [8] According to Dr. Eikelboom, understanding the mechanisms for aspirin resistance should lead to ...

Aspirin works to relieve pain and fever by blocking an enzyme called cyclooxygenase (COX). COX plays a major role in ...

This syndrome is referred to as aspirin-induced asthma (AIA). The pathogenesis of AIA has implicated both the lipoxygenase (LO) and the cyclooxygenase (COX) pathways. By inhibiting the COX pathway ...

"The findings uncover a new way in which the immune system is suppressed, limiting T cells from fighting cancer spread. This ...

Researchers have made new discoveries about aspirin’s mechanism of action and cellular targets. Their findings suggest potential interplay between cyclooxygenase enzyme, or COX, and indoleamine ...

All of these can cause stomach upset, but usually less so than aspirin. It is now known that all of these drugs block the activities of cyclooxygenase (COX), enzymes that act early in the pathways ...