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Karin Pelka is the 2025 recipient of the AAAS Martin and Rose Wachtel Cancer Research Award for her work with these critical ...
The BioNTech SE acquisition of CureVac N.V. brings together complementary technologies, as both are developing mRNA ...
ARV-393 demonstrated significant single-agent activity in models of nodal T-follicular helper cell lymphoma, ...
SSRIs enhance CD8 T cell antitumor activity by inhibiting SERT, an immune checkpoint in tumors, suggesting potential repurposing for cancer immunotherapy. High intratumoral SERT levels correlate with ...
Dr. Jared Weiss explained that radiation for lung cancer may ease symptoms or aim to cure, with newer targeted forms ...
In a study that further corroborated these observations, scientists found that cyclic fasting in mice improved their antitumor responses mediated by natural killer (NK) cells. 4 The results, published ...
The Antitumor Assessment (ATA) Core provides support for early discovery and in vivo testing of antitumor detection and therapeutic agents. The Core provides resources, professional and technical ...
The metabolic status of cytotoxic T cells or lymphocytes controls antitumor immunity. These cells are sensitive to the tumor microenvironment (TME). The TME can inhibit the anticancer immune ...
An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve immunotherapy. Courtney and his team sought to exploit this property of TIP to ...