In this double-blind trial, researchers randomized 180 patients (minimum age, 16) with annular skin lesions (erythema migrans) of ≥5 cm in diameter to 1 of 3 treatments: a single 2-g dose of ...

2 The classic presentation is that of a well-circumscribed annular erythematous patch or plaque with a slightly raised border. Common locations include the hands and feet. Most cases are readily ...