In motile animal cells, such as fibroblasts or macrophages ... During the S (DNA-replication) phase of the cell cycle, each centriole cylinder duplicates through the budding of a new cylinder ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles. Cell division is one of the most fundamental ...

Examples include inhibitors of cell cycle progression ... Transplantation of transformed cells into "humanized" animal models, such as mice whose hematopoietic systems have been reconstituted ...