For instance, in normal, healthy mice, the agouti genes are kept in the "off" position by the epigenome, which attaches methyl groups to the corresponding regions of DNA, resulting in the DNA's ...

The dominant A allele -- the variant form of a gene that gives rise to specific physical traits -- restricts black pigmentation, and its presence in wild mice results in an "agouti mouse" with a ...

Restoring Agouti function to C57BL/6N embryonic stem cells allows visualization of embryonic stem cell–derived mice by coat color (Supplementary Note) and permits the recovery of pure inbred ...

Much of what's known about the epigenetics of pregnancy comes from experiments with mice, specifically a group of genetically identical agouti mice. When these mice are exposed to certain ...

They started with pairs of fat yellow mice known to scientists as agouti mice, so called because they carry a particular gene—the agouti gene—that in addition to making the rodents ravenous and yellow ...

The research showed that without agouti, these mice would be jet black. Various genes involved in color and patterns in animal coats have been identified in the lab, but this is the first time the ...

Randy Grenier, Waltham, Massachusetts [Editor's note: For more on the agouti mice, see "A Tale of Two Mice" in Editors' Picks.] Q: If BPA has the same effect on humans as it did the mice in your ...

Team member Stefan Laurent sequenced a gene called Agouti, which has been linked to fur color, in all 481 of the mice. He found seven mutations that had become more common in the light enclosures ...

The mice are Agouti Viable Yellow, naturally occurring mutants, which, though genetically identical, have coats that vary in color—a phenomenon that researchers have long studied as an example of ...

darker forest mice. The changes were caused by changes to the agouti protein, found in all vertebrates, which controls pigment-creating cells called melanocytes. The research showed that without ...

Jirtle’s group studies mice known as viable yellow agouti mice. Scientists use them to gauge how diet, chemicals and other environmental conditions affect gene activity in animals, probably ...