There’s a lot gone on since [the last guideline was published in] 2014, and it now doesn’t reflect best practice,’ said ...

Prophylactic trimethoprim-sulfamethoxazole lowered serious infection risk in patients with ANCA-associated vasculitis, ...

The prophylactic efficacy of TMP-SMX was significantly higher in subgroups with baseline lymphopenia, azotemia, microscopic polyangiitis, or relapsed AAV.

A middle-aged man was diagnosed with necrotizing scleritis associated with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and responded well to rituximab therapy ...

When Robert Atchison and his colleagues at the University of Pittsburgh first stumbled across adeno-associated viruses (AAV) in 1965, they initially supposed they were merely defective byproducts ...

Adeno-associated viral (AAV) vectors are viruses used to deliver gene therapies to different cells. They are considered one of the field’s most effective delivery tools. AAVs show particular ...

UK cost-effectiveness organisation NICE has recommended routine NHS use of a recently-approved therapy for two forms of ANCA-associated vasculitis (AAV) – oral complement C5 inhibitor Tavneos ...

Risk factors for mortality in AAV-ILD included age, a history of smoking, a UIP pattern, acute exacerbations of ILD, and the microscopic polyangiitis subtype.

This in silico approach aims to increase the fitness of clinical adeno-associated virus (AAV) capsids to make gene therapies more economically viable for patients. Developing AAV capsids with ...