For decades, researchers have produced numerous AD drugs targeting amyloid beta only for them to fail in clinical trials. Scientists have only shifted focus more recently to developing anti-tau ...

The aggregation of these proteins, which are known as "amyloid-beta," give rise to a chain of events that ... plays in microglia and we also unravel the mechanism behind why its inhibition is so ...

Researchers at the University of Cincinnati found that new monoclonal antibody drugs may slow cognitive decline by increasing levels of a critical brain protein called amyloid-beta 42 (Aβ42 ...

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always ...

Amyloid cardiomyopathy (cardiac amyloidosis ... [Yancy 2013;15a; Ash 2020;3b] Dialysis-associated amyloidosis, caused by aggregation of beta-2-microglobulin. [Yancy 2013;15a] Of the cardiomyopathy ...

The aggregation of these proteins, which are known as "amyloid-beta", give rise to a chain ... we also unravel the mechanism behind why its inhibition is so beneficial", says McManus.

The ‘NLRP3 inflammasome’ is like a control switch. In Alzheimer’s disease, its activation triggers an inflammatory response ...

The aggregation of these proteins, which are known as "amyloid-beta," give rise to a chain ... we also unravel the mechanism behind why its inhibition is so beneficial," says McManus.