Aggrecan is the major proteoglycan in the articular cartilage. This molecule is important in the proper functioning of articular cartilage because it provides a hydrated gel structure (via its ...

Treatment of Lower Back Pain Utilizing a Biomimetic Aggrecan Injection (K. Barbee, M. Marcolongo, E. Vresilovic, and B. Schauer) Download Poster - [PDF] Abstract: Degenerative disc disease of the ...

Aggrecan is one of the main components of the ECM and the key component of the PNs. 43, 44 It is the largest member of the lectican family and carries up to 100 negatively charged chondroitin ...