The proportion of patients with ACLF grade 3 was lower in the recompensated group vs. the decompensated group. 1-year survival rates were higher in recompensated vs. decompensated patients.

16.7%), which was more pronounced among those with ACLF grade 2 (23.7% vs. 14.8%) and grade 3 (43.3% vs. 29.9%). While younger patients had better survival across all grades of ACLF, Alukal noted ...

The study group reported ACLF of any grade in 31.0% of patients at enrollment. Of these, 54.2% presented with ACLF grade 1, 24.9% had ACLF grade 2, and 20.9% had ACLF grade 3 (meaning three or ...

7% The risk of death post-transplant even in ACLF grade 2 or 3 was not significantly different (P=0.051) from those who have decompensated cirrhosis, Jalan reported. "In patients with ACLF grade 3 ...

The device treats patients with Acute-on-Chronic Liver Failure (ACLF) grade 2 and 3, a life-threatening condition affecting patients with cirrhosis characterized by multiorgan failure and high ...

This is an interventional, double blind, randomized, and placebo- controlled study of 1 dose regimen of HALPC intravenously infused in patients newly diagnosed with ACLF grade 1 or 2 on top of ...

eGenesis has gained US Food and Drug Administration (FDA) clearance on an investigational new drug (IND) application for a genetically engineered porcine (pig) liver. The organ is designed for use ...

As part of the Phase 1 trial, up to twenty (20) patients with ACLF (Grade 2 to Grade 3) and hepatic encephalopathy (≤ Grade 3) and ineligible for transplant will be enrolled across multiple U.S ...

The Phase I trial plans to enrol 20 patients with ACLF (Grade 2 to Grade 3) and hepatic encephalopathy (≤ Grade 3), who are ineligible for transplant, across multiple US centres. eGenesis ...