However, SV-AUC was better than SEC-MALS in creating a detailed "map" of the distribution of the genetic and viral particles in the AAV vector. The study suggested that "SEC-MALS could be ...

An AAV sample with predominantly filled capsids ... without external standard curves. On the other hand, AUC separates particles based on their sedimentation rates, providing detailed physical ...

That deal is worth $35 million per year in average annual salary, but he reportedly could have gotten an even bigger deal in AAV from the Baltimore Orioles. Roch Kubatko of MASN reported that the ...

Gene therapy represents one of the fastest growing biotherapeutics worldwide, with AAV at the forefront. This rapid growth is constantly challenging CMC approaches, from manufacturing through release ...

Beckman Coulter introduced the first AUC sample characterization instrument to help the scientific community power new discoveries. That tradition continues into the 21st century with the new ...

Safe and effective gene therapy strategies depend on robust and reliable adeno-associated virus (AAV) mediated therapeutic gene delivery. However, scaling up AAV manufacturing to obtain sufficient ...