Although recognizing the descriptive benefits of ‘party hub’ and ‘date hub’ nomenclature we call clathrin and AP2 ‘pathway hubs’ because this does not immediately ascribe any behaviour ...

The way that gametocytes regulate their formation involves a transcription factor, AP2-G. When AP2-G is turned on, allowing for gene expression, parasites become gametocytes in the human host.

Our group discovered the CAPA pathway while identifying endocytic regulators ... We found that the assembly of AP2 is assisted by two chaperones: AAGAB and CCDC32. Our current research focuses on ...