The original Thorn test employing intramuscular injection of crude ACTH has proved to be unsatisfactory because of the large number of false-negative responses. At present, on the basis of the ...

2 minute read TIME December 12, 1960 12:00 AM GMT-5 ...

People with typical adrenal function experience a rise in cortisol levels after the ACTH injection. People with adrenal insufficiency typically do not see a rise in cortisol levels.

The plasma ACTH activity varied from 200 to 400 milliunits per 100 ml. by the method of Hume and Nelson 2 (normal, 0), and on 1 occasion was 630 milliunits by another method 3 (Table 1).

Shifting from non-standard therapy to ACTH would increase response from 8% to 39% (95% CI, 17-67) and from 8% to 38% (95% CI, 15-68) for a switch to oral steroids.

Cite this article Branco, R., Amoretti, C., Korb, C. et al. 522 Low and Stardard Doses of Synthetic Acth in the Assessment of Adrenal Function of Children with Septic Shock. Pediatr Res 68 (Suppl ...

In a recent study evaluating the function of the HPA axis in psoriatic patients versus controls, no marked differences were observed in ACTH and cortisol responses in a CRH infusion test, but ...