The basal extracellular ACh levels were 1.80±0.54 (fmol/10 μL) and 4.16±0.60 (fmol/10 μL) in the mPFC and HIP, respectively. The effects of Re on DA in the mPFC and HIP ...

It has been reported that clozapine increases ACh release in mPFC, NAC, and STR, using microdialysis with neostigmine to increase basal ACh to detectable levels (Parada et al. 1997).

Functional connection between hippocampus and cortex modulates anxiety Date: February 3, 2010 Source: Cell Press Summary: A new study demonstrates that cooperation between the hippocampus, best ...

A new study demonstrates that cooperation between the hippocampus, best known for its critical role in learning and memory, and a principal downstream cortical target modulates anxiety-related ...

These therapeutic effects are thought to involve modulation of the medial prefrontal cortex (mPFC), a brain region implicated in depression pathology. This study presents preliminary ...

“Our study suggests that double-projecting hippocampal neurons can facilitate synchronized neural activity in the mPFC and amygdala that is implicated in learned fear,” he said. “It is by modulating ...

Chinese researchers have reported that slow rhythmic fluctuations in brain activity—theta oscillations in the medial prefrontal cortex (mPFC)–entorhinal cortex (EC) circuit—play an essential ...

The team then injected a virus into some of the mice that inserts a gene called GluR4 into mPFC neurons.GluR4 amplifies transmission of electrical signals – a key step in strengthening ...