A tractor-trailer burst into flames after crashing on a stretch of I-81 in Virginia, backing up traffic for hours and sending ...

Due to a multivehicle crash on Interstate 81 northbound at the 272.5 mile marker, both lanes are shut down as of 6:50 p.m.

Two people are dead after a head-on collision on Interstate 81 in Greene County Monday morning. According to the Tennessee ...

A New Jersey truck driver was injured when his tractor-trailer crashed on Interstate 81 in Shenandoah County on Saturday.

Update as of 9:08 a.m.: All lanes have reopened. Syracuse, N.Y. — Interstate 81 South traffic in Syracuse is being rerouted after a crash Tuesday morning, dispatchers said. At 7:36 a.m., a hit-and-run ...

Two people were killed in a crash that happened on Interstate 81 in Greene County early Monday, according to Tennessee ...

The scene on Interstate 81 was nothing short of apocalyptic on Saturday after a tractor trailer caught fire in Shenandoah ...

One woman died when she was struck by a vehicle on Highway 81 near Madison on Saturday. Around 5:45 a.m., first responders ...

A tractor-trailer crash involving multiple vehicles shut down Interstate 81 southbound near Exit 5 (Greencastle/Waynesboro) ...