Sarepta Therapeutics said a patient taking its treatment for Duchenne muscular dystrophy has died from acute liver failure. The pharmaceutical firm said that "acute liver injury is a known possible side effect of Elevidys.

The young man died of acute liver injury, a known side effect, Sarepta said in a statement. But the company said the “severity” of the patient’s case had not previously been seen with the therapy, called Elevidys. It’s the first known patient death with the therapy, which has been used in more than 800 patients, the company said.

Shares of Sarepta Therapeutics have struggled for the past year due to concerns about the commercial potential of its gene therapy and broader pipeline. Safety hadn’t been a major worry for investors—