IgG4-related sclerosing disease is a condition that may affect a single organ or multiple organs at once, causing lumps, swellings, and masses to form and leading to widespread inflammation.

In patients with IgG4-related disease, the serum IgG4 concentration is typically high and often very, very high. Example, elevated up to five or 10 times the upper limit of normal is not unusual ...

IgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for treat ...

Key takeaways: B-cell depletion with inebilizumab reduced flare risk for pancreatic and/or biliary IgG4-related disease. It also reduced overall glucocorticoid use for disease control in both groups.

He, L., Zhou, Y., Wang, Q.T., Liu, J. and Ma, J.P. (2025) Two Pathological Patterns in Different Stages of the Same Disease. Journal of Biosciences and Medicines, 13, 189-195. doi: ...

IgG4-related disease is very uncommon, seen in approximately five people per 100,000 in the U.S., Stone and colleagues observed. It currently has no specific approved therapy: ...

IgG4-related disease Pipeline Development Activities. The IgG4-related disease report provides insights into different therapeutic candidates in Phase II, and Phase III stages.

Immunoglobulin G4-related disease (IgG4-RD) is a chronic, systemic, immune-mediated, fibroinflammatory disease which can affect numerous and generally multiple organs of the body. 1 It is a ...

Beamon set out on a journey, and 26 doctors, 37 procedures and more than 17 years later, a rheumatologist finally cracked the confounding code: She had immune disorder IgG4-related disease, and ...

Dublin, June 03, 2025 (GLOBE NEWSWIRE) -- The "IgG4-Related Disease - Market Insight, Epidemiology, and Market Forecast - 2034" report has been added to ResearchAndMarkets.com's offering. This ...

The Food and Drug Administration (FDA) has approved Uplizna ® (inebilizumab-cdon) for the treatment of immunoglobulin G4-related disease (IgG4-RD) in adult patients.. The approval for IgG4-RD was ...

The disease mimics other diseases due to the heterogeneous and unpredictable inflammatory flares that can occur.3 Over time, IgG4-RD can affect virtually any organ system.1 ...