Kamloops is a city in south-central British Columbia, Canada, at the confluence of the North and South Thompson Rivers, which join to b…Kamloops is a city in south-central British Columbia, Canada, at the confluence of the North and South Thompson Rivers, which join to become the Thompson River in Kamloops, and east of Kamloops Lake. The city is the administrative centre for the Thompson-Nicola Regional District, a region of the British Columbia Interior.