Zilwaukee is a city in Saginaw County in the U.S. state of Michigan. The 2020 census places the population at 1,534. The city is adjacent to a…Zilwaukee is a city in Saginaw County in the U.S. state of Michigan. The 2020 census places the population at 1,534. The city is adjacent to and was created from Zilwaukee Township. It is the home of the Zilwaukee Bridge.