Little River is a 60-mile river in Tennessee which drains a 380-square-mile area containing some of the most spectacular scenery in the southeastern United States. The first 18 miles of the river are located within the borders of the Great Smoky Mountains National Park. For the remaining 42 miles, the Little flows out of the mountains through Blount County to join th…Little River is a 60-mile river in Tennessee which drains a 380-square-mile area containing some of the most spectacular scenery in the southeastern United States. The first 18 miles of the river are located within the borders of the Great Smoky Mountains National Park. For the remaining 42 miles, the Little flows out of the mountains through Blount County to join the Tennessee River at Fort Loudon Lake in Knox County.